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Description

Memantine as an augmenting agent for severe pediatric OCD

PLoS One 9 , e84703 (2014)

Monitoring focuses on IGF-1, glucose handling, thyroid context, lipids, and fluid-retention symptoms

Limitations include limited large-scale human clinical evidence, challenges in extrapolating in-vitro concentrations to in-vivo contexts, stability sensitivities (light, heat, alkaline pH), and variability in supplier purity